The A673T (“Icelandic”) mutation in APP is associated with protection against Alzheimer's disease and age-related cognitive decline. This knock-in rat model carries the Icelandic mutation and a ...
Creating better, more reliable rodent models of Alzheimer’s disease has been a struggle for researchers. On October 19 in Molecular Neurodegeneration, scientists led by Bart De Strooper at KU Leuven, ...