Not all cancer mutations are equal: Mutation strength in a single gene shapes tumor behavior

Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced ...
Cancer Therapy Advisor

Similarities Found in Cancer Driver Gene Mutations of Felines and Humans

In this study, researchers aimed to characterize the mutational landscape of the tumors of domestic cats to determine whether similarities to humans could translate to the clinic.
Yahoo

Mutations tied to cancer risk found in 17 million Americans, researchers warn

Some 17 million Americans are living with genetic mutations tied to an increased risk of getting cancer, Cleveland Clinic researchers warned Monday. And the more than 3,400 mutations identified – ...

Cancer’s Deadly Paradox: How Tumors Break Their Own DNA To Keep Growing

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

Penn launches Lynch syndrome center as cases of the cancer-risk condition have nearly tripled

Nearly 1,000 patients seeking care at Penn Medicine have a genetic condition known as Lynch syndrome — a diagnosis linked to higher risks of several cancers. That’s almost triple the number diagnosed ...

UCSD researcher to lead international team probing cancer mutations

UC San Diego professor Ludmil Alexandrov will lead an international team of scientists awarded $25 million to research cancer mutations. The award comes from Cancer Grand Challenges, a collaboration ...
Science Daily

The surprising cancer link between cats and humans

Scientists have mapped the genetics of cancer in cats for the first time at scale, uncovering major overlaps with human ...
Medical Xpress

Order of cancer-driving mutations affects the chance of tumor development, study shows

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals. These are the findings published on 3 December in ...
News Medical

Machine learning tool predicts cancer treatment response based on genetic mutations

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic mutations influence cancer treatment outcomes-insights that could help doctors ...
Labroots

How Mutations in a Cancer-Linked Gene Can Promote Tumors

A gene known as CTNNB1 encodes for a crucial protein called β-catenin, which has an important role in controlling tissue repair and cell growth. If this gene and its protein are dysfunctional, it can ...
The Conversation

What is a ‘cancer gene’? How genetic mutations lead to cancer

Sarah Diepstraten receives funding from the National Health and Medical Research Council, Cure Cancer Australia and My Room Children's Cancer Charity. John (Eddie) La Marca receives funding from ...