Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely ...

One of the most revolutionary discoveries of the century, the CRISPR gene-editing system is built on a bacterial defense mechanism that allows scientists to make precise edits to DNA. Now scientists ...

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key ...

Scientists at Cambridge have demonstrated a new method for potentially fighting a form of leukemia, by targeting overactive enzymes that can lead to the disease. If the results of mice tests carry ...

Scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be 'undruggable ...

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients. The exact mechanisms of ...

Researchers at Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that a new target of rapamycin (TOR) inhibitor, ...

A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions ...

Researchers have succeeded in understanding the biosynthetic mechanisms for the production of the natural product cyanobacterin, which is produced in small quantities by the cyanobacteria Scytonema ...

(Nanowerk News) Industrial biocatalysis is mainly used for the production of pharmaceuticals and special chemicals. To advance this process, researchers are working on new process technologies. In ...