To support drug discovery, a new study has revealed fundamental features of the transcription cycle in the bacteria that causes tuberculosis.

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene ...

Timing of gene expression Demonstrating their technique in mouse embryonic stem cells, the researchers found that they could calculate approximately when a particular region starts to be transcribed, ...

This breakthrough allows researchers to visualize where individual genes are active at the cellular level—information that has long been missing due to technical limitations in tea biology. By ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

When a gene is active, there is cellular machinery that transcribes the sequence of that gene from DNA into messenger RNA. This is a fundamental cellular process that is essential to the proper ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.