The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...
Neurons stochastically generated up to eight different versions of a protein regulating neurotransmitter release, which could vary how they communicate with other cells. Neurons are talkers. They each ...
To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice — all at the same time — ...
A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...
Glutamate is a chemical messenger in the brain that plays a crucial role in learning and memory. It also functions to regulate mood. In this article, we provide a definition of glutamate and explain ...
After each neurotransmitter release, MK801, an open-channel blocker that can only block a channel that has been activated, decreases initial current (which has been normalized for wild type and mutant ...
The latticework of extracellular protein that surrounds brain cells forms a particularly dense mesh around fast-spiking interneurons. Why do these cells need such thick coats? In the July 17 Nature ...