In those precious weeks before a woman even realizes she's pregnant, an embryo will have already developed a neural tube, a hollow structure made of cells which will eventually become the brain and ...

Folate is a naturally occurring form of vitamin B found in food, while folic acid is synthetically produced and used in fortified foods and supplements. It is well known that taking folic acid before ...

New research provides intriguing insight into how the nervous system forms during very early embryonic development. The study sheds light on a process called neural tube closure which, when disrupted, ...

NTDs are severe congenital malformations that result from failure of neural tube closure by the 28th day of gestation. The neural tube forms the early brain and spine. The two most common NTDs are ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 17 (Aug. 14, 2001), pp. 9683-9687 (5 pages) The forebrain overgrowth mutation (fog) was originally ...

Pregnancy can bring a lot of questions about your baby’s development. Learning about potential health concerns is an important part of getting ready for parenthood and making sure your baby gets the ...

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving ...

Only 38% of women in a recent UK survey took folic acid while trying for a baby, despite long‑standing NHS advice. Why are so ...

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving ...

A multi-institutional research team has developed a novel folic acid-resistant neural tube defect mouse model of the human condition by silencing the Slc25a32 gene, and, in most of the mutant mice, ...