We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. After being described in 2018, this molecule took our team on a six-year journey ...

By Dr. Priyom Bose, Ph.D. A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

The inactivation or deletion of the gene CHD2 and its product is associated with pediatric neurodevelopment disorders and pediatric epilepsy. But too much CHD2 can also cause problems—and the balance ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

In a recent study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has been elucidated, offering new insights into potential therapeutic targets.