A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

Autoimmune gastritis is a chronic progressive inflammatory condition that results in the replacement of the parietal cell mass by atrophic and metaplastic mucosa. A complex interaction of ...

Correspondence to Dr Lauren Pringels, Department of Physical and Rehabilitation Medicine, Ghent University Hospital, Ghent, Belgium; Lauren.Pringels{at}UGent.be Despite the high prevalence of tendon ...

Chronic graft-versus-host disease (GVHD) can inflict debilitating tissue injury and puts patients at high risk for death from infections. For several decades, little progress was made in the treatment ...

Cardiovascular disease remains the leading cause of mortality worldwide, necessitating deeper insights into its molecular underpinnings beyond genetic predisposition. Epigenetic modifications, ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...

Like all forms of cancer, lung cancer is defined by uncontrolled cell division caused by loss of physiological tissue homeostasis and failure of apoptotic cell death mechanisms. Aberrant cell ...

Angioedema is basically swelling of the deeper layers of the skin. This is due to accumulation of fluids caused by an allergic reaction. Pathogenesis of the types of angioedema has been studied ...

The research in Singh laboratory is broadly focused on the pathophysiology of iron in disorders of the brain and the eye. Current interests in the lab include: Iron cycling in the eye. Pathophysiology ...

The Northwestern University Feinberg School of Medicine Mesulam Center for Cognitive Neurology and Alzheimer’s Disease is currently recruiting participants to be part of their ‘SuperAging Research ...

This course is part of The Applied Sciences of Oncology (ASO) distance-learning course.Aim: To provide an understanding of the basic molecular biology and pathogenesis of malignancies.ObjectivesUpon ...