The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in their development. New insights into how maternal and paternal DNA is ...

Maize serves as a vital model species for advancing our understanding of plant biology, yet many mysteries remain about the intricate processes ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...